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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd926fd9f863c7aaec9186081188333a05fa729011ca5e571137dcbf5775759' 
  AND token = 'joXZ+d/e3S+qTKMIUw77GazPyOv0b9iUP73RFqaA/wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}