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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129921d4a44a1b0ae329cfcd037861f3823bbfe9e43f823791479a9e3143caba' 
  AND token = 'sBG6b7sxv6N9Qo9bOjHrOy37icTHRdhcMO4o2FVXvHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}