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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d534bad0e2fd4e7bda599d7cb0a10c4f19fd86432ef90cddc295effca83a1bd' 
  AND token = 'mDv5CxRJqwoR3A1to6SQeC/sLC5F3Sh1XuWH8wCVZmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}