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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453e52c852dbadd94d50564472427f6ad6697f6b45a5df6614e7ef2d28df1cb7' 
  AND token = 'DdEFix+6V8ql2Fl7aK0+58YemLuxgdBpNx7VKBEo59w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}