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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a9d326a8db9161dd86db71153f3f34c3ec8042bd362d65726a0446a1c80bff4' 
  AND token = 'CPzyaQCjvE0p3jT6Jce4IJ0w1PmLDyeNldy0PSeLL/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}