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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c294fb22506d5f262a29e748cec479bd91b823f09c17822ea129df8a42bfc9' 
  AND token = 'AJguss7cIwJ2eX3CCo5B95tdW6r7zYKRFl4BCH6WS50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}