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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cd7ae4d1b31c303e5498f1dfa99453e63ce20a396d90e7fcd1ab54c934e1500' 
  AND token = 'Dw1f1Ft/06DTdJcPksGoAEXxMfSQ5KUl5O14qsfFqE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}