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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2234c6640e6f064f5628d35375b460742790e6ed229240db05e92dd5c67983' 
  AND token = 'zGXjbhuJlJmmctjS1L+qtvTOjRsfY+jkI2hDa2q4cmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}