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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08850beb720b06b6f1c2195c93e12a8fe9fd14b1500947e950c7d5cbe2cb507c' 
  AND token = 'Os+3IsWcxFwGNyl2DqFiiVcFoHqkXzCe8NeI3P+D5go=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}