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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b864d03e2e7d973abde6f1bfc0a3798d19cbf33cabf187912c3acc6980ba0138' 
  AND token = 'tlojZCI8oXSw9k5KM6yjyYPE5QVrgyQsJl8PXUqXaQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}