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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2212c80788185acebbc213414ea0242e23f17e3eca4a2b079a61a58370c7e47f' 
  AND token = 'NuVEpKm+0ioCT0SIWFuF2VWo5Pcf0Pn5C8ZKGDNWJYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}