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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a938df40c1ff78d505a09e145b3e278ec6b0f4100650b4523aeb592ba6b53d21' 
  AND token = 'aaXl+H2EFBVNuJQxdz4zWNiPfiBtB4WtoRb9Yw3CiKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}