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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7527241fcd58dbb8c5f64b6d8cd7fc97474df730999f4f1a7d527a5aeb4c47f8' 
  AND token = 'pI8thGQZ453RPIlEj8tz9khusCdAbjtxPM0m0PBC9Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}