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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25442d050c30a96e1e6b8f732a243014aec82c26a4f6bc7d17d1c2cac1636f3' 
  AND token = 'T/6GcEQ/A+f1gqyTQf62O0nzM5dsAo5fymddZfMpfzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}