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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2f54b7a7cb77038df06f6e2b98536b8b87b4dda97e3f8ebee41a8cd66180db' 
  AND token = 'gXDW/ePW1MU4RThTbY0h1xD3rwuQ/XlTixi+tMhSV6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}