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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbcb8670b9705d98b464a3f37bc037700d0fb5dbf45ac010199b7ae7f88e2b89' 
  AND token = '6UjQvLrNoHH3Vky/D4eNtpmCOA0sS7GUZEllAk7z2Ng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}