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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441f0e7367c09160aa85c102c15e3ee477e8b80ff394ac3ea67c32d87ee7a51a' 
  AND token = 'QV0mF98udpT8UX1Ll/x1zDSLoJjpCk6UyQZ9kqAjamo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}