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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887690f7579021f88d90a841c0da83229d9905b4bb56aa69962ff53ac1468ecc' 
  AND token = '499H1PiTjLno7wGAPa9I/N/GE6akjmBuZtV1DZvFLdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}