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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd187fd7bb2852b1fbe25302546e9953aa7d8eb20f47d2e82cb54115754cb20cb' 
  AND token = 'H5m2jrF+peFvscPuVs2aa3GteDC7opJhoQmA1G+dNUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}