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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4856572ea48080e39f05e01350e2e076ae56f1456de9485b349f46ea09118d' 
  AND token = 'qZO4k6UNsWxdLX2GCxvrO4huJbrbTYCGxE3bL9S6vOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}