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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4135dd6c012367e3c419bfe3ffb2830c3415b548d41609c5bd8cbc2a4b82c75' 
  AND token = 'KH+jkDklsxp+Cd9hIp9eAA5RRDK5nHCEYPG9K9vUb58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}