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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28aedcff8f69a48cc50cdf35e6df7da921248ef14d22c7fbd896b7129e3b942e' 
  AND token = '2RIafXPPiL+VoBlJln7LIf7Fl+2q+WZ5ubUNWwwVhsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}