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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f6fc4f90042b8fffe5e497519121f5e99e48cc6bcea940e1f66ab016c541cb' 
  AND token = 'J1TjAOYlhAK7XmeN2aTyQtV5nZYZq/4QX378tIf2RkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}