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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72403299d8a97063cc19ff98d414a0a3841784a312c83b4f5445af1eb19b86e9' 
  AND token = 'V0/glOLgd0cMPGmrPYtIhZEuecYS+l4zaDC22NrfWtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}