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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9375d7e5082fdc748031e80d854cab0782cf3b2dba73b332af649ff8580774e3' 
  AND token = 'RaehR8VPAnzrFTGNNCJGKZDhRp+rTxyTxrgio8H8gpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}