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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79aa7b579a7cb6d9a86d56663ac8a221d1750ba72d7c047cdd4de4de916a2563' 
  AND token = 'ttzMC0EdTaF7Uk68jypkuVG4E6FLQIhExLqQ4/kWtI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}