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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '737c06f78f9993b5b5b98a5efaf42ee96948bbd7a75b5ed84a40a84c679e4f01' 
  AND token = '0bVEvBE1LVSlA7c1MiUOICUbypZLWkPb9JPkN3DEdaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}