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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f25d334f27660800c34cb1a3c3419992d4f93fcd0ddf77b3f7d42fca7c23253' 
  AND token = 'GRQ72Tnr4sAisCSpTRokOaifgZ1NjZ1DKJtDFLDiMXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}