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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1dd22c589490807079c0bcf843a9117a57cfdf5ade478b8b3a820f0dc9f858' 
  AND token = '5XvUEw30zJT18bVAnkw/FL+OEPvkXyBkOV1vUd+F0po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}