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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f61ac8ac2f122a4a6cdf6540e1e3d32740882f2ea783ca4ddf315778a03cad2' 
  AND token = 'zDgm5S9UPocreDNmd9wJfN5/cYVLh9LAm5YWj9PEgSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}