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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331dd257f4ac29d46eae6b1cdecb0ee6c5371a46a288300b108f448e28c723b5' 
  AND token = 'YsCkzz4m1rwz8pW8UAFcOb9Fcn5WRkB9zWh90/EqwvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}