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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e20de5a2016371f2a9f143e96cc0c64741ea671601f487074dc338328e898c' 
  AND token = 'ABZylswE9z4Sdg05xAr48Gz+c3zhhe5nE8alJwy/UTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}