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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb42cad6251929f76eb706d7e9d0b8670c62988b105690e9821a9f1b566f790' 
  AND token = 'mzOQVZxsv0Whll5G3ROXPL7VHw6hc8krwIwyMqJXZGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}