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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca66d280284db74e9ed552c7ded289926cef984e284ede9ea45ce9f13deab07' 
  AND token = 'Gx6np+JkOf6fTDQV5ynYBIPKryHNS9N4kss1v+2ICcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}