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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44cfdefb19e46a2824bef1a9faded9b98dba93606d74df8b5f9f7d8f0299424' 
  AND token = 'EjU0BMR4P2ndMm1AjdjDdiZQAl9Z00WSJonj3Fow0BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}