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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125ccf3dfc19ca063046d9d5a8afe1ebd679b5cbc7197d5cf48331dce19f07d8' 
  AND token = '8tOlXxKYP01nCeDVufm2wx9bMukU7LbmbLyPTH3iApw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}