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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1423a938036629caf9a4e42830310ab1ea9bbf1ec1ebf2561a736442724b7610' 
  AND token = 'nElII6Xg5SsD/fFIgK9BZEAiQdx+WE1mzRRn8EZ3OXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}