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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c01d73fda9404686e409b71ae14decb8ef0f3f494da962a727da6c68a5c3f6' 
  AND token = 'XaE8+OEpAbV4jkAeB5/KQuKBMMTtb0yESGDLHmddR3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}