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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7327ddf0c6aed59023390df4ab804e0ad0d7d9a69c7d57d584cc81815021483f' 
  AND token = 'z2WG2pwD2wh/Vbe07yB6Oy7qL9NHEvdMdYdIBsyAVC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}