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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e40afac2766dd100272af3d897bb5343048c5347f395980f0fcceff448cc78c' 
  AND token = 'HDqg5dHRzMKKSZZQS3XZ3dxszk+WZNmKOVn/SK4zkBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}