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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd272271f24f2059ad9f5c994be4365551d8a7668f54619ff9a61c1d440efb86f' 
  AND token = 'ddXH4uLkUwRnPH1kskUm+BlSKMoo/ZRSYMu4qZ0o4Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}