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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b50768296f09bd434058df87d4b3af51d86952de70e98fb22a7b1ab6f7c465' 
  AND token = 'as6Ye0gU8tUeWc/bX3mGzn/lAG3Trx9XF1Lec5m/ObI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}