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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174831c55beb885b7a6af8bbbde083d29bc49f9d9392e1ff5f7b5ae002e57d8b' 
  AND token = 'fKjc8cVkOmAMwh528aSWNCRJX6nbrUjDB52qrOkWTEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}