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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734222e5061b5b971c1211e71247263d7c5c324532057bf9e6e2f228542f0a3e' 
  AND token = 'cXow6tpInueVxSHyIsU8/Z5HMk1wM9PjqUnZw/jGdGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}