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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147b6f79d4574d49bb7a05f05ead5ecfcf59ce48bf894941464a2e5c99d02060' 
  AND token = 'X+XNqT5GPpneXeidCsfR9k0nUDeo8gWp05363nF/KpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}