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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12812bfaf3998174360c97c3fe93f88e5047140dc8b4acba618119897c9e6265' 
  AND token = '02o73vBx4lhM9V4oAw2bM/9cKX7aF+6GxTxMrGjVU6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}