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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '166a1e59a411caf021737f8a46ef86c9ab9ef87737c7251e55b3bb20426e0e71' 
  AND token = 'm3kgQiJZTYCKJ9k1y+aSD8jOkJQ5BntLLK1JulygTko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}