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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10337d186582b72f3f1aa6e9e132770ef0ddc880f9d230421f1b5b652810c928' 
  AND token = 'NaXqAiM1r1jbn7CKoN3nEfGz50BPCQUEqBuyj25PAf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}