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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f26603a3ac603aa13536b51dcf5e88a41854d41906fdcba004fe95a3d930de54' 
  AND token = 'tPVSOerWGw+VpIfRVZtycytNX4p6ChyBEf4zGo+BYLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}