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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c10659f28e25a848a1063b0f1aa24cfd27057666cd52c023c9d460429a3c53' 
  AND token = 'vJb1lX8tPnBgt830wBlsbkgpDF0zIHxAl9z0XDZnKdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}